Lo studio presentato al congresso sin bologna 2019
Kuzik® was well tolerated: in a numerical scale from 1 to 10 the average score was 9,5 ( range 8 -10) ; the compliance of patients was optimal, no side effect related to product were reported and no weight gain in patients occurred. A clear improvement of the patient’s asthenia should be noted. Regarding efficacy, at the end of treatment , in total population all parameters analyzed were significantly improved.
Our study clearly demonstrated the benefits, safety, and good tolerability of Kuzik® in the prophylaxis of migraine, with and without aura
Lo studio e’ stato presentato come poster ( 289-93) al congresso nazionale sisc napoli 2019
Dall’analisi dei risultati emerge vi è la riduzione uguale o superiore al 50% della frequenza di giorni
cefalea/mese nel 31.7% dei pazienti, una significativa riduzione del consumo medio di analgesici e
del punteggio NRS. Non sono stati riferiti effetti collaterali durante la terapia.
dimostrano l’efficacia del kuzik come trattamento di profilassi per l’ ESA, associata ad una buona
Lo studio e’ stato presentato al congresso stresa headache 2019
Our study clearly demonstrated the benefits, safety, and good tolerability of Kuzik® in the prophylaxis of migraine, with and without aura. This study confirms the data obtained in the previous trial and highlights the positive data obtained with Kuzik® twice daily in patients with chronic disease. The use of this medication should be taken in consideration as a good practice in this setting of patients.
The journal of headache and pain 2017, 18 (suppl 1):111 p187
Efficacy of KUZIK® in the prophylaxis of migraine without aura: a retrospective observational study
A migraine without aura is the most common type of migraine headache (about 60% to 80% of all migraines). In recent years there is growing interest in the use of nutraceuticals for the prevention of migraine, as there are no specific drugs for this indication. A new kudzu based food supplement (Kuzik), thanks to its innovative mechanism of action, has attracted our interest in this use.
Materials and Methods
January and April 2017, 30patients with migraine without aura were treated with Kuzik, once a day for 2 months, recruited in various neurological structures including university centers, general hospitals, territorial structures and private outpatient clinic; for all patients, the diary was completed and full fill the headache card (IHS criteria). Patients were evaluated at baseline and after 2 months regarding number of crisis, headache days and VAS (Visual Analogue Scale): data relative to efficacy and tolerability were collected. Patient’s characteristics: 25 female and 5 male; median age 34 (range 22-56); median years of disease 9,4 (range 2-30) and previous treatments 1,2 (range 1-2). At the baseline average number of crisis was 4 (range 2-10) , headache days 7,4 (range 3-14) and medium VAS 7,1 (range 5-10).
Kuzik was well tolerated: in a numerical scale from 1 to 10 the average score was 8 (range 6 -10); the compliance of patients was optimal, no side effect related to product were reported and no weight gain in patients occurred. Regarding efficacy, at the end of treatment, all parameters analyzed were significantly improved: average number of crisis was 1,2 (range 0-3), headache days 2 (range 0-5) and medium VAS 1,9 (range 0-4) .
Our study has clearly demonstrated the benefits, safety, and good tolerability of Kuzik in the prophylaxis of migraine without aura and the use of this medication should be taken in consideration as a good practice in this setting of patients. Data from our study are encouraging to be confirmed by further investigations.