The Journal of Headache and Pain 2018: 19 (Supp 1): 80
Efficacy of KUZIK® in the prophylaxis of migraine without aura: a case report
E.Pucci1, R. Galante2.
1.Headache Science Center - fake watches University Consortium for the Study of Adaptive Disorders and Headache (UCADH), Department of Brain and Behavioral Sciences, University of Pavia, IRCCS “C. Mondino” Pavia.2. Gam FarmaSrl. Milan.
A migraine without aura is the most common type of migraine headache (about 60% to 80% of all migraines). In recent years there is growing interest in the use of nutraceuticals for the prevention of migraine, as there are no specific drugs for this indication. A new kudzu based food supplement (Kuzik), thanks to its mechanism of action, has attracted our interest in this use.
Materials and Methods
25 year old woman. Familial family history of headache (paternal line). swiss replica watches Onset of school age. Gradual increase after the menarche. Diagnosis according to the criteria ICHD-III beta-version: migraine without aura.
Frequency: 4 crisis / month. VAS (Visual Analogue Scale): 7. Duration of the crisis: 24-72 hours. Disabling crisis on the first day of the menstrual cycle. Triggering factors: menstruation, ovulation, psycho-physical stress. drugs used as needed: fans with partial benefit. No preventive therapies.
Total days / month with migraine: 10. Total number of symptomatic administrations:
12. The patient performed complementary therapy with Kuzik 2 tablets in the morning on a fast.
Kuzik was well tolerated: on a numerical scale from 1 to 10 the average score was 8 ;patient compliance was optimal, no side effects related to the product were reported, and no weight gain occurred in the patient. As far as efficacy is concerned, at the end of the treatment all the parameters analyzed were significantly improved: the average number of seizures was 2 (range 0-4), days with headache 4 (range 0-12) and medium VAS 3 (range 0-7).It should be noted that there was no disabling crisis at the beginning of menstruation and that there was a reduction, above all, of the intensity of the crises, associated with frequency and duration.
Our study has clearly demonstrated the benefits, safety, Montblanc replica and good tolerability of Kuzik in the prophylaxis of migraine without aura and the use of this medication should be taken in consideration as a good practice in this setting of patients. Data from our study are encouraging to be confirmed by further investigations.